Cellagentech/Repro-ThiPSC | Enhance reprogramming efficiency cocktail/K8447-500/0.5mL of 1000x
商品编号:
K8447-500
品牌:
cellagentech
市场价:
¥3380.00
美元价:
2028.00
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
ProductDescription
Repro-ThiPSC(i.e.SMC4inreference1)isacocktailoffoursmallmoleculesofspecificsignalingpathwayinhibitors.ItcanbeaddeddirectlyinmediatoincreasereprogrammingefficiencyofsomaticcellstoiPSCs,andtoimproveexpansionandmaintenanceofhiPSCsunderbothwithfeedercellsandfeeder-freeconditions.Itcanbeusedincombinationwithanyofthewidelyusedreprogramminggeneexpressionsystems(e.g.retro/lenti-viral,episomal,mRNA,orproteins)toenhancethereprogrammingsomaticcellstoiPScells.Thisprocessisrobust,efficientandcanbeeasilyscaled-up1-3.
Technicalinformation:
CocktailFormulation: 1000xDMSOstocksolution | 5mMofThiazovivin(ROCKinhibitor), 0.4mMofPD325901(MEKinhibitor), 2mMofSB431542(TGF-ß1inhibitor),and 1mMofCHIR99021(GSK3ßinhibitor) | |
Purity: | >98%(foreachcompound) |
ShippingCondition:Theproductisshippedinaglassvialatambienttemperature.
Storage:StoreDMSOsolutionat-20oC.
Usage:DiluteRepro-ThiPSCstocksolution(1000x)at1:1000intobasiciPSCinductionmediatomake1xRepro-ThiPSCmedia.
Reference:
1. | ValamehrB,etal.Anovelplatformtoenablethehigh-throughputderivationandcharacterizationoffeeder-freehumaniPSCs.ScientificReports.2012.2:213. |
2. | LiW,etal.Generationofhuman-inducedpluripotentstemcellsintheabsenceofexogenousSox2.StemCells.2009.27(12):2992-3000. |
3. | KawamataM,etal.Generationofgeneticallymodifiedratsfromembryonicstemcells.PNAS.2010.107,14223-14228. |
品牌介绍
Cellagen Technology 公司位于美国加州San Diego,该公司致力于干细胞相关产品的研发和生产。基于多年为世界*的生物公司提供OEM产品的经验,目前Cellagen Technology公司利用自身优势,拓展了原有产品线,推出了以StemRegenin 1(SR1)为代表的多种自有品牌产品。 NamePriceCat # (Powder)Cat # (10 mM in DMSO)Pathway/Target7,8-Dihydroxyflavone1173C7181-10N/ATrkBA7696622023C2769-10N/AAMPKA83-011513C2831-2C2831-2sTGF-β/ALK4,5,7Abiraterone1853C2247-2C2247-2sP450-CYP17BEZ235833C2392-2C2392-2sPI3K, mTORBIX-012941513C2491-5C2491-5sEpigenetics/G9a HMTCHIR990213553C2447-2C2447-2sGSK3β CP-6905501343C2716-2C2716-2sJAK1,2,3Cyclopamine2193C2925-2C2925-2sHedgehog/SmoDAPT1853C3178-5C3178-5sNotch/γ-secretaseForskolin1853C3677-10N/AAdenylate cyclaseFTY7201173C3897-5C3897-5sS1P receptorsGDC-09411513C4321-5C4321-5sPI3KHh-Ag1.53043C4412-2C4412-2sHedgehog/SmoINCB0184241853C4622-2C4622-2sJAK1/2IWP-31853BackorderBackorderWntKHS1011853C5471-5C5471-5sNeural differentiationLDE2252363C5332-2C5332-2sHedgehog/SmoLDN-1931893723C5361-2C5361-2sBMP/ALK2,3Leukadherin-1#VALUE!C5385-2C5385-2sCD11b, CD18LY2940022193C5929-5C5929-5sPI3KP7C32363C7723-10N/Aneurogenic, neuroprotectivePD03259013723C7303-2C7303-2sMEK1, MEK2PD03329912193C7306-2C7306-2sCdk4, Cdk6PS481343C7748-5C7748-5sPDK1Pyrintegrin3383C7974-1C7974-1sES cell survivalR4062193C7406-2C7406-2sSykR7883723C7788-5C7788-5sSykRapamycin2193C7272-5C7272-5smTORReversine1173C7383-2C7383-2sA3 Adenosine ReceptorRO49290972703C7649-2C7649-2sNotch/γ-secretaseSB4315421513C7243-5C7243-5sTGF-β/ALK4,5,7SF16703723C7316-2C7316-2spTENSitagliptin1513C7482-5C7482-5sDPP-4SRT17202363C7781-2C7781-2sSIRT1StemRegenin1 (SR1)3723C7710-1C7710-1sAryl hydrocarbon receptorSU54022703C7854-1C7854-1sFGFRThiazovivin3553C8442-1C8442-1sROCKUrsolic Acid1853C8776-10N/ASTAT3VX-6801173C8916-10N/AAurora kinaseWnt-C592703C7641-2C7641-2sWntXAV9392703C9289-2C9289-2sWntY-276321853C9127-2C9127-2sROCKhuman Activin A5423P4228-1031910 µg37383P4228-1002199100 µghuman BMP-4 3723P4267-1021910 µg25483P4267-1001499100 µghuman bFGF 3383P4234-5019950 µg23783P4234-5001399500 µgmouse LIF 3383P6543-1019910 µg23783P6543-1001399100 µghuman Wnt-3a 3723P4968-1021910 µg
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